MolNFT v1 · #182250 · protein

PYL10 bound to the aba pan-antagonist antabactin

7MLD · Abscisic acid receptor PYL10: “PYL10 bound to the aba pan-antagonist antabactin”. X-ray diffraction, 1 ligand (ZLG), 1 pocket (best druggability 0.77). MolNFT v1 #182250 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7MLD
Type: protein
Length: 153 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Abscisic acid receptor PYL10
UniProt: Q8H1R0
Ligands: ZLG
Pockets: 1 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Abscisic acid receptor PYL10	protein	153	27% helix, 42% strand	Q8H1R0

Ligands and binding sites

ZLG · antabactin · ligand · chains A
CIT · Citric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	357	0.77	0.87	37	ZLG

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

7MLD · PYL10 bound to the ABA pan-antagonist antabactin · the same entry in another collection · chain A against A, TM-score 1.00
Q8H1R0 · AlphaFold monomer V2.0 prediction for abscisic acid receptor PYL10 (Q8H1R0) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8H1R0
Elsewhere: RCSB PDB 7MLD · PDBe 7MLD · UniProt Q8H1R0

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