Vascular katp channel: KIR6.1 SUR2B propeller-like conformation 2

Structure

electron microscopy · 4 distinct chains.

Ligands and binding sites

• ATP · Adenosine-5'-triphosphate · ligand · 5 copies · chains A, D, B, C, E
• GBM · 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl) sulfamoyl]phenyl}ethyl)-2-methoxybenzamide · ligand · chains E
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7MJP · Vascular KATP channel: Kir6.1 SUR2B propeller-like conformation 2 · the same entry in another collection · chain E against E, TM-score 1.00
• Q63563 · AlphaFold monomer V2.0 prediction for ATP-binding cassette sub-family C member 9 (Q63563) · a predicted model of the same protein · chain E against A, TM-score 0.96
• Q63664 · AlphaFold monomer V2.0 prediction for ATP-sensitive inward rectifier potassium channel 8… · a predicted model of the same protein · chain C against A, TM-score 0.83

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q63664
• Every structure of UniProt Q63563
• Elsewhere: RCSB PDB 7MJP · PDBe 7MJP · UniProt Q63664 · UniProt Q63563