MolNFT v1 · #182154 · protein
Human CTPS2 bound to inhibitor R80
7MIH: “Human CTPS2 bound to inhibitor R80”. Electron microscopy, 3 ligands (ZG4, UTP, MG). MolNFT v1 #182154 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7MIH
- Type
- protein
- Length
- 1,936 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9NRF8
- Ligands
- ZG4, UTP, MG
Structure
electron microscopy · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, E | — | protein | 484 | — | Q9NRF8 |
Ligands and binding sites
- ZG4 · N-(1-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}cyclopropyl)-5-(6-ethoxypyrazin-2-yl)pyridine-2-carboxamide · ligand · 4 copies · chains A, B, C, E
- UTP · Uridine 5'-triphosphate · ligand · 4 copies · chains A, B, C, E
- MG · Magnesium ion · metal · 4 copies · chains A, B, C, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NRF8
- Elsewhere: RCSB PDB 7MIH · PDBe 7MIH · UniProt Q9NRF8
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