MolNFT v1 · #182139 · protein
X-ray structure of yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound (compound 20)
7MI1 · Chimera protein of dynein and endolysin: “X-ray structure of yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound…”. X-ray diffraction, 20 pockets (best druggability 0.87). MolNFT v1 #182139 on…
- PDB
- 7MI1
- Type
- protein
- Length
- 2,628 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chimera protein of dynein and endolysin
- UniProt
- P36022, D9IEF7
- Pockets
- 20 · best druggability 0.87
Structure
x-ray diffraction · 1 distinct chain · 56% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chimera protein of dynein and endolysin | protein | 2628 | 56% helix, 10% strand | P36022, D9IEF7 |
Pockets
20 pockets found on a 1 Å grid, 19 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 877 | 0.87 | 0.89 | 120 | empty |
| 2 | 759 | 0.84 | 0.87 | 98 | empty |
| 3 | 365 | 0.78 | 0.87 | 59 | empty |
| 4 | 1068 | 0.77 | 0.79 | 91 | empty |
| 5 | 1013 | 0.76 | 0.79 | 97 | empty |
Compared structures
- 7MI1 · X-ray structure of yeast dynein motor domain in the presence of a pyrazolo-pyrimidi… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P36022
- Every structure of UniProt D9IEF7
- Elsewhere: RCSB PDB 7MI1 · PDBe 7MI1 · UniProt P36022 · UniProt D9IEF7
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