MolNFT v1 · #182041 · protein

Structure of yeast UBR1 in complex with UBC2 and monoubiquitinated N- degron

7MEY: “Structure of yeast UBR1 in complex with UBC2 and monoubiquitinated N- degron”. Electron microscopy, 2 ligands (Z3V, ZN). MolNFT v1 #182041 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7MEY
Type: protein
Length: 2,033 residues
Chains: 5
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P19812, P0CG47, P06104
Ligands: Z3V, ZN

Structure

electron microscopy · 5 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	1731	—	P19812
C	—	protein	71	—	P0CG47
B	—	protein	153	—	P06104
D	—	protein	75	—	P0CG47
F	—	protein	3	—	—

Ligands and binding sites

Z3V · 2-(ethylamino)ethane-1-thiol · ligand · chains C, B, D
ZN · Zinc ion · metal · 7 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7MEY · Structure of yeast Ubr1 in complex with Ubc2 and monoubiquitinated N-degron · the same entry in another collection · chain C against C, TM-score 1.00
P19812 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase UBR1 (P19812) · a predicted model of the same protein · chain A against A, TM-score 0.93
P06104 · AlphaFold monomer V2.0 prediction for ubiquitin-conjugating enzyme E2 2 (P06104) · a predicted model of the same protein · chain B against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19812
Every structure of UniProt P0CG47
Every structure of UniProt P06104
Elsewhere: RCSB PDB 7MEY · PDBe 7MEY · UniProt P19812 · UniProt P0CG47 · UniProt P06104

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