MolNFT v1 · #181785 · protein
Crystal structure of the mertk kinase domain in complex with inhibitor MIPS15692
7M5Z: “Crystal structure of the mertk kinase domain in complex with inhibitor MIPS15692”. X-ray diffraction, 1 ligand (YR7). MolNFT v1 #181785 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7M5Z
- Type
- protein
- Length
- 527 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q12866
- Ligands
- YR7
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 263 | — | Q12866 |
| B | — | protein | 264 | — | Q12866 |
Ligands and binding sites
- YR7 · 2-(butylamino)-N-[1-(3-fluoropropyl)piperidin-4-yl]-4-{[(1r,4r)-4-hydroxycyclohexyl]amino}pyrimidine-5-carboxamide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7M5Z · Crystal Structure of the MerTK Kinase Domain in Complex with Inhibitor MIPS15692 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12866
- Elsewhere: RCSB PDB 7M5Z · PDBe 7M5Z · UniProt Q12866
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