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Ligand · YR7

YR7 · 2-(butylamino)-N-[1-(3-fluoropropyl)piperidin-4-yl]-4-{[(1r,4r)-4-hydroxycyclohexyl]amino}pyrimidine-5-carboxamide

YR7, 2-(butylamino)-N-[1-(3-fluoropropyl)piperidin-4-yl]-4-{[(1r,4r)-4-hydroxycyclohexyl]amino}pyrimidine-5-carboxamide (C23 H39 F N6 O2, 450.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
YR7
Formula
C23 H39 F N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

YR7 in 2 structures; the first of them:

  • 7M5Z · Crystal Structure of the MerTK Kinase Domain in Complex with Inhibitor MIPS15692 · YR7 A901 · binds LEU593, GLY594, GLU595, VAL601, ALA617, LYS619, ILE650, LEU671 and 9 more
  • 7M5Z · Crystal structure of the mertk kinase domain in complex with inhibitor MIPS15692 · YR7 A901 · binds LEU593, GLY594, VAL601, ALA617, LYS619, ILE650, LEU671, PRO672 and 6 more

Residues it binds most

LEU 4, MET 4, GLY 4, ALA 4, LYS 4, PHE 4, PRO 4, VAL 4, ASP 3, ILE 3 (residue and the binding sites it lines).

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