MolNFT v1 · #181489 · protein
Crystal structure of the BCL6 btb domain in complex with oicr-12694
7LWG: “Crystal structure of the BCL6 btb domain in complex with oicr-12694”. X-ray diffraction, 2 ligands (YN7, UNX). MolNFT v1 #181489 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LWG
- Type
- protein
- Length
- 243 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P41182
- Ligands
- YN7, UNX
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 122 | — | P41182 |
| B | — | protein | 121 | — | P41182 |
Ligands and binding sites
- YN7 · 5-{(5S)-1-[2-({3-chloro-6-[(2S)-2,4-dimethylpiperazin-1-yl]-2-fluoropyridin-4-yl}amino)-2-oxoethyl]-4-oxo-4, 6,7,8-tetrahydro-1H-dipyrrolo[1,2-A:2',3'-d]pyrimidin-3-yl}-3,4-difluoro-2-hydroxybenzamide · ligand · 2 copies · chains A, B
- UNX · Unknown atom or ion · ion · 4 copies · chains A, B
- GOL · Glycerol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7LWG · Crystal structure of the BCL6 BTB domain in complex with OICR-12694 · the same entry in another collection · chain A against A, TM-score 1.00
- P41182 · AlphaFold monomer V2.0 prediction for B-cell lymphoma 6 protein (P41182) · a predicted model of the same protein · chain A against A, TM-score 0.32
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41182
- Elsewhere: RCSB PDB 7LWG · PDBe 7LWG · UniProt P41182
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