MolNFT v1 · #181474 · protein
Structural and biochemical insight into assembly of molecular motors involved in viral DNA packaging
7LW0 · Terminase small subunit: “Structural and biochemical insight into assembly of molecular motors involved in viral DNA packaging”. X-ray diffraction, 7 pockets (best druggability 0.76). MolNFT v1 #181474 on GenesisL1: 3D structure…
- PDB
- 7LW0
- Type
- protein
- Length
- 448 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Terminase small subunit
- EC
- 3.6.4.-
- UniProt
- P03707
- Pockets
- 7 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H | Terminase small subunit (EC 3.6.4.-) | protein | 56 | 52% helix, 11% strand | P03707 |
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 415 | 0.76 | 0.86 | 38 | empty |
| 2 | 171 | 0.48 | 0.77 | 26 | empty |
| 3 | 120 | 0.43 | 0.77 | 18 | empty |
| 4 | 104 | 0.39 | 0.76 | 19 | empty |
| 5 | 88 | 0.35 | 0.74 | 14 | empty |
Interfaces
15 interfaces between chains.
- D–H · 651 Ų buried · 8 hydrogen bonds · protein-protein
- B–E · 639 Ų buried · 8 hydrogen bonds · protein-protein
- B–G · 631 Ų buried · 6 hydrogen bonds · protein-protein
- C–H · 619 Ų buried · 9 hydrogen bonds · protein-protein
- D–F · 580 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 7LW0 · Structural and Biochemical Insight into Assembly of Molecular Motors Involved in Viral… · the same entry in another collection · chain H against H, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03707
- Elsewhere: RCSB PDB 7LW0 · PDBe 7LW0 · UniProt P03707
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