MolNFT v1 · #180767 · protein
Crystal structure of the first bromodomain (BD1) of human BRD2 bound to volasertib
7LAK: “Crystal structure of the first bromodomain (BD1) of human BRD2 bound to volasertib”. X-ray diffraction, 1 ligand (IBI). MolNFT v1 #180767 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LAK
- Type
- protein
- Length
- 120 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- U3KQA6
- Ligands
- IBI
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 120 | — | U3KQA6 |
Ligands and binding sites
- IBI · N-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7LAK · Crystal structure of the first bromodomain (BD1) of human BRD2 bound to volasertib · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt U3KQA6
- Elsewhere: RCSB PDB 7LAK · PDBe 7LAK · UniProt U3KQA6
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