MolNFT v1 · #180743 · protein
Crystal structure of dihydrofolate reductase from mycolicibacterium smegmatis in complex with sddc-0001565 inhibitor
7L9T: “Crystal structure of dihydrofolate reductase from mycolicibacterium smegmatis in complex with sddc-0001565…”. X-ray diffraction, 2 ligands (QKJ, SO4). MolNFT v1 #180743 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7L9T
- Type
- protein
- Length
- 156 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- I7FC10
- Ligands
- QKJ, SO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 156 | — | I7FC10 |
Ligands and binding sites
- QKJ · 3-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl) oxy]propoxy}phenyl)propanoic acid · ligand · chains A
- SO4 · Sulfate ion · ion · 2 copies · chains A
- DMS · Dimethyl sulfoxide · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7L9T · Crystal Structure of Dihydrofolate reductase from Mycolicibacterium smegmatis in complex… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I7FC10
- Elsewhere: RCSB PDB 7L9T · PDBe 7L9T · UniProt I7FC10
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