MolNFT v1 · #180712 · protein
Crystal structure of human GPX4-U46C mutant K48A
7L8R · Isoform cytoplasmic of phospholipid hydroperoxide…: “Crystal structure of human GPX4-U46C mutant K48A”. X-ray diffraction, 1 ligand (SCN). MolNFT v1 #180712 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7L8R
- Type
- protein
- Length
- 328 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Isoform cytoplasmic of phospholipid hydroperoxide glutathione peroxidase
- EC
- 1.11.1.12
- UniProt
- P36969
- Ligands
- SCN
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Isoform cytoplasmic of phospholipid hydroperoxide glutathione peroxidase (EC 1.11.1.12) | protein | 164 | 35% helix, 20% strand | P36969 |
Ligands and binding sites
- SCN · Thiocyanate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 93 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 7L8R · Crystal structure of human GPX4-U46C mutant K48A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P36969
- Elsewhere: RCSB PDB 7L8R · PDBe 7L8R · UniProt P36969
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