MolNFT v1 · #18061 · protein

Crystal structure of osmotin, a plant antifungal protein

1PCV: “Crystal structure of osmotin, a plant antifungal protein”. X-ray diffraction, 4 pockets (best druggability 0.30). MolNFT v1 #18061 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1PCV
Type: protein
Length: 410 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Osmotin
UniProt: P14170
Pockets: 4 · best druggability 0.30

Structure

x-ray diffraction · 1 distinct chain · 13% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Osmotin	protein	205	13% helix, 37% strand	P14170

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	62	0.30	0.74	12	empty
2	83	0.30	0.72	19	empty
3	73	0.29	0.72	13	empty
4	54	0.25	0.73	15	empty

Interfaces

1 interface between chains.

A–B · 146 Å² buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 16 disulfide (disulfide).

Compared structures

1PCV · Crystal structure of osmotin, a plant antifungal protein · the same entry in another collection · chain A against A, TM-score 1.00
P14170 · AlphaFold monomer V2.0 prediction for osmotin (P14170) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P14170
Elsewhere: RCSB PDB 1PCV · PDBe 1PCV · UniProt P14170

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