MolNFT v1 · #283072 · protein

AlphaFold monomer V2.0 prediction for osmotin (P14170)

P14170: “AlphaFold monomer V2.0 prediction for osmotin (P14170)”. 3 pockets (best druggability 0.55). MolNFT v1 #283072 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P14170
Type: protein
Length: 246 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x6c2cC0486fb44B18D7Df3279EE7D533F42858Eba
Molecule: Osmotin
UniProt: P14170
Pockets: 3 · best druggability 0.55

Structure

1 distinct chain · 12% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Osmotin	protein	246	12% helix, 33% strand	P14170

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	72	0.55	0.87	22	empty
2	114	0.35	0.73	21	empty
3	53	0.32	0.77	12	empty

Modifications

Observed in the structure: 8 disulfide (disulfide).

Compared structures

1PCV · Crystal structure of osmotin, a plant antifungal protein · an experimental structure of the same protein · chain A against A, TM-score 0.82
1PCV · Crystal structure of osmotin, a plant antifungal protein · an experimental structure of the same protein · chain A against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P14170
Elsewhere: UniProt P14170 · AlphaFold DB P14170

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