MolNFT v1 · #180499 · protein
HIV integrase core domain (in) in complex with dimer-spanning ligand
7L1P: “HIV integrase core domain (in) in complex with dimer-spanning ligand”. X-ray diffraction, 3 ligands (R2A, SO4, IOD). MolNFT v1 #180499 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7L1P
- Type
- protein
- Length
- 274 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q76353
- Ligands
- R2A, SO4, IOD
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 136 | — | Q76353 |
| B | — | protein | 138 | — | Q76353 |
Ligands and binding sites
- R2A · (2-{[3-(4-{2-[(3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzene-1-carbonyl) amino]ethyl}piperazine-1-carbonyl)phenyl]ethynyl}-5-methyl-1-benzofuran-3-yl)acetic acid · ligand · chains A, B
- SO4 · Sulfate ion · ion · 7 copies · chains A, B
- IOD · Iodide ion · ion · 6 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7L1P · HIV Integrase Core domain (IN) in complex with dimer-spanning ligand · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q76353
- Elsewhere: RCSB PDB 7L1P · PDBe 7L1P · UniProt Q76353
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.