MolNFT v1 · #180337 · protein

Dihydrodipicolinate synthase (dhdps) from C.JEJUNI, H56N mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site

7KWF: “Dihydrodipicolinate synthase (dhdps) from C.JEJUNI, H56N mutant with pyruvate bound in the active site and…”. X-ray diffraction, 1 ligand (3VN). MolNFT v1 #180337 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7KWF
Type: protein
Length: 1,793 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q9PPB4
Ligands: 3VN

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, F	—	protein	296	—	Q9PPB4
C	—	protein	305	—	Q9PPB4
D	—	protein	304	—	Q9PPB4
E	—	protein	296	—	Q9PPB4

Ligands and binding sites

3VN · (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid · ligand · 3 copies · chains B, F, A, C, D, E
ACT · Acetate ion · additive · 2 copies · chains B, F
PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains C, D
PGE · Triethylene glycol · additive · 2 copies · chains E, F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7KWF · Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56N mutant with pyruvate bound in… · the same entry in another collection · chain F against F, TM-score 1.00
Q9PPB4 · AlphaFold monomer V2.0 prediction for 4-hydroxy- tetrahydrodipicolinate synthase (Q9PPB4) · a predicted model of the same protein · chain F against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9PPB4
Elsewhere: RCSB PDB 7KWF · PDBe 7KWF · UniProt Q9PPB4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.