MolNFT v1 · #180174 · protein
Crystal structure of HIV-1 reverse transcriptase in complex with (E)- 4-(3-chloro-5-(2-CYANOVINYL)PHENOXY)-3-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-YL)ETHOXY)PHENYL sulfurofluoridate (JLJ709)
7KRC: “Crystal structure of HIV-1 reverse transcriptase in complex with (E)…”. X-ray diffraction, 1 ligand (X2J). MolNFT v1 #180174 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7KRC
- Type
- protein
- Length
- 957 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03366
- Ligands
- X2J
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 548 | — | P03366 |
| B | — | protein | 409 | — | P03366 |
Ligands and binding sites
- X2J · 4-{3-chloro-5-[(E)-2-cyanoethenyl]phenoxy}-3-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenyl sulfurofluoridate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7KRC · Crystal Structure of HIV-1 Reverse Transcriptase in Complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03366
- Elsewhere: RCSB PDB 7KRC · PDBe 7KRC · UniProt P03366
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