MolNFT v1 · #17996 · protein
Cyclodextrin glucanotransferase
1PAM: “Cyclodextrin glucanotransferase”. X-ray diffraction, 1 ligand (CA), 8 pockets (best druggability 0.74). MolNFT v1 #17996 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1PAM
- Type
- protein
- Length
- 1,372 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cyclodextrin glucanotransferase
- EC
- 2.4.1.19
- UniProt
- P05618
- Ligands
- CA
- Pockets
- 8 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 23% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Cyclodextrin glucanotransferase (EC 2.4.1.19) | protein | 686 | 23% helix, 30% strand | P05618 |
Ligands and binding sites
- CA · Calcium ion · metal · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 433 | 0.74 | 0.83 | 64 | empty |
| 2 | 405 | 0.72 | 0.83 | 63 | empty |
| 3 | 1061 | 0.71 | 0.75 | 117 | empty |
| 4 | 398 | 0.65 | 0.79 | 36 | empty |
| 5 | 418 | 0.65 | 0.78 | 37 | empty |
Interfaces
1 interface between chains.
- A–B · 720 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05618
- Elsewhere: RCSB PDB 1PAM · PDBe 1PAM · UniProt P05618
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