MolNFT v1 · #179937 · protein
Phosphoinositide 3-kinase gamma bound to a thiazole inhibitor
7KKE: “Phosphoinositide 3-kinase gamma bound to a thiazole inhibitor”. X-ray diffraction, 1 ligand (WJV). MolNFT v1 #179937 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7KKE
- Type
- protein
- Length
- 842 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P48736
- Ligands
- WJV
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 842 | — | P48736 |
Ligands and binding sites
- WJV · N-[2-(3,3-dimethylbutoxy)ethyl]-N'-{4-methyl-5-[(pyridin-4-yl)ethynyl]-1,3-thiazol-2-yl}urea · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7KKE · Phosphoinositide 3-Kinase gamma bound to a thiazole inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P48736
- Elsewhere: RCSB PDB 7KKE · PDBe 7KKE · UniProt P48736
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