MolNFT v1 · #179822 · protein
Dihydrodipicolinate synthase (dhdps) from C.JEJUNI, H56W mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site
7KH4: “Dihydrodipicolinate synthase (dhdps) from C.JEJUNI, H56W mutant with pyruvate bound in the active site and…”. X-ray diffraction, 2 ligands (3VN, MG). MolNFT v1 #179822 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7KH4
- Type
- protein
- Length
- 1,793 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9PPB4
- Ligands
- 3VN, MG
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, F | — | protein | 296 | — | Q9PPB4 |
| B, D | — | protein | 304 | — | Q9PPB4 |
| E | — | protein | 297 | — | Q9PPB4 |
Ligands and binding sites
- 3VN · (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid · ligand · 3 copies · chains A, F, B, C, D, E
- MG · Magnesium ion · metal · 19 copies · chains A, B, C, E, F
- EDO · 1,2-ethanediol · additive · 33 copies · chains A, F, B, C, D, E
- ACT · Acetate ion · additive · 13 copies · chains A, B, C, D, E, F
- PEG · Di(hydroxyethyl)ether · additive · 10 copies · chains A, F, B, C, D, E
- PG4 · Tetraethylene glycol · additive · 6 copies · chains A, B, C, D, E, F
- PGE · Triethylene glycol · additive · 4 copies · chains B, D, E
- GOL · Glycerol · additive · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7KH4 · Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56W mutant with pyruvate bound in… · the same entry in another collection · chain F against F, TM-score 1.00
- Q9PPB4 · AlphaFold monomer V2.0 prediction for 4-hydroxy- tetrahydrodipicolinate synthase (Q9PPB4) · a predicted model of the same protein · chain C against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9PPB4
- Elsewhere: RCSB PDB 7KH4 · PDBe 7KH4 · UniProt Q9PPB4
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