MolNFT v1 · #179714 · protein
Crystal structure of the bromodomain (bd) of human bromodomain and phd finger-containing transcription factor (bptf) bound to compound 6 (HZ01052)
7KDW: “Crystal structure of the bromodomain (bd) of human bromodomain and phd finger-containing transcription factor…”. X-ray diffraction, 1 ligand (WCV). MolNFT v1 #179714 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7KDW
- Type
- protein
- Length
- 227 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q12830
- Ligands
- WCV
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 113 | — | Q12830 |
| B | — | protein | 114 | — | Q12830 |
Ligands and binding sites
- WCV · cyclopropyl[7-({2-[(prop-2-yn-1-yl)amino]pyrimidin-4-yl}amino)-3,4-dihydroquinolin-1(2H)-yl]methanone · ligand · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7KDW · Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12830
- Elsewhere: RCSB PDB 7KDW · PDBe 7KDW · UniProt Q12830
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