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MolNFT v1 · #179373 · protein

Crystal structure of DLC8 in complex with panoramix tq peptide

7K3L · Dynein light chain 1, cytoplasmic: “Crystal structure of DLC8 in complex with panoramix tq peptide”. X-ray diffraction. MolNFT v1 #179373 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7K3L
Type
protein
Length
98 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Dynein light chain 1, cytoplasmic; Protein panoramix
UniProt
Q24117, Q9W2H9

Structure

x-ray diffraction · 2 distinct chains · 34% helix, 42% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADynein light chain 1, cytoplasmicprotein8638% helix, 40% strandQ24117
BProtein panoramixprotein120% helix, 58% strandQ9W2H9

Ligands and binding sites

  • EDO · 1,2-ethanediol · additive · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 632 Ų buried · 14 hydrogen bonds · protein-protein

Compared structures

  • 7K3L · Crystal structure of dLC8 in complex with Panoramix TQ peptide · the same entry in another collection · chain A against A, TM-score 1.00
  • Q24117 · AlphaFold monomer V2.0 prediction for dynein light chain 1, cytoplasmic (Q24117) · a predicted model of the same protein · chain A against A, TM-score 0.99
  • Q9W2H9 · AlphaFold monomer V2.0 prediction for protein panoramix (Q9W2H9) · a predicted model of the same protein · chain B against A, TM-score 0.30

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