UniProt Q24117
Dynein light chain 1, cytoplasmic (Q24117)
Dynein light chain 1, cytoplasmic (UniProt Q24117): 36 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q24117
- Protein
- Dynein light chain 1, cytoplasmic
- Experimental structures
- 36
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
37 records of Q24117 in the MolNFT archive: 36 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1RHW | The solution structure of the pH-induced monomer of dynein light chain LC8 from Drosophila | solution nmr | A | — | — |
| 1RHW | The solution structure of the pH-induced monomer of dynein light chain LC8 from drosophila | solution nmr | A | — | — |
| 2P2T | Crystal structure of dynein light chain LC8 bound to residues 123-138 of intermediate chain IC74 | x-ray diffraction | A | — | — |
| 2P2T | Crystal structure of dynein light chain LC8 bound to residues 123-138 of intermediate chain IC74 | x-ray diffraction | A | — | — |
| 2PG1 | Structural analysis of a cytoplasmic dynein Light Chain-Intermediate Chain complex | x-ray diffraction | A, B, C, D | — | — |
| 2PG1 | Structural analysis of a cytoplasmic dynein light chain- intermediate chain complex | x-ray diffraction | A, B, C, D | — | — |
| 3BRI | Crystal Structure of apo-LC8 | x-ray diffraction | A | — | — |
| 3BRI | Crystal structure of apo-LC8 | x-ray diffraction | A | — | — |
| 3BRL | Crystal Structure of LC8 S88E / Swa | x-ray diffraction | A | — | — |
| 3BRL | Crystal structure of LC8 S88E / swa | x-ray diffraction | A | — | — |
| 3DVH | LC8 Point mutant K36P | x-ray diffraction | A, B, C | — | — |
| 3DVH | LC8 point mutant K36P | x-ray diffraction | A, B, C | — | — |
| 3DVP | Pak1 peptide bound LC8 | x-ray diffraction | A, B | — | — |
| 3DVP | PAK1 peptide bound LC8 | x-ray diffraction | A, B | — | — |
| 3DVT | Biochemical and structural characterization of the PAK1- LC8 interaction | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3DVT | Biochemical and structural characterization of the PAK1- LC8 interaction | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3E2B | Crystal structure of Dynein Light chain LC8 in complex with a peptide derived from Swallow | x-ray diffraction | A | — | — |
| 3E2B | Crystal structure of dynein light chain LC8 in complex with a peptide derived from swallow | x-ray diffraction | A | — | — |
| 3FM7 | Quaternary Structure of Drosophila melanogaster IC/Tctex-1/LC8; Allosteric Interactions of Dynein… | x-ray diffraction | E, F | — | — |
| 3FM7 | Quaternary structure of drosophila melanogaster IC/TCTEX-1/LC8; allosteric interactions of dynein… | x-ray diffraction | E, F | — | — |
| 3GLW | Quaternary Structure of Drosophila melanogaster IC/Tctex-1/LC8; Allosteric Interactions of Dynein… | x-ray diffraction | A | — | — |
| 3GLW | Quaternary structure of drosophila melanogaster IC/TCTEX-1/LC8; allosteric interactions of dynein… | x-ray diffraction | A | — | — |
| 4QH7 | LC8 - Ana2 (159-168) Complex | x-ray diffraction | A, B, E, F | — | — |
| 4QH7 | LC8 - ANA2 (159-168) complex | x-ray diffraction | A, B, E, F | — | — |
| 4QH8 | LC8 - Ana2 (237-246) Complex | x-ray diffraction | A, B, E, F, G, H | — | — |
| 4QH8 | LC8 - ANA2 (237-246) complex | x-ray diffraction | A, B, E, F, G, H | — | — |
| 5E0L | LC8 - Chica (415-424) Complex | x-ray diffraction | A | SO4 | — |
| 5E0L | LC8 - chica (415-424) complex | x-ray diffraction | A | — | — |
| 5E0M | LC8 - Chica (468-476) Complex | x-ray diffraction | A | SO4 | — |
| 5E0M | LC8 - chica (468-476) complex | x-ray diffraction | A | — | — |
| 7K3J | Crystal structure of dLC8 in complex with Panoramix TQT+TQ peptide | x-ray diffraction | A, C, E, G, I, K | SO4 | 3 (best 0.64) |
| 7K3J | Crystal structure of DLC8 in complex with panoramix TQT+TQ peptide | x-ray diffraction | A, C, E, G, I, K | SO4 | — |
| 7K3K | Crystal structure of dLC8 in complex with Panoramix TQT peptide | x-ray diffraction | A | — | — |
| 7K3K | Crystal structure of DLC8 in complex with panoramix tqt peptide | x-ray diffraction | A | — | — |
| 7K3L | Crystal structure of dLC8 in complex with Panoramix TQ peptide | x-ray diffraction | A | — | — |
| 7K3L | Crystal structure of DLC8 in complex with panoramix tq peptide | x-ray diffraction | A | — | — |
| Q24117 | AlphaFold monomer V2.0 prediction for dynein light chain 1, cytoplasmic (Q24117) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 4 records
Experiment against prediction
- 2PG1 chain D against the predicted model Q24117: TM-score 0.99, RMSD 0.30 Å
- 2PG1 chain D against the predicted model Q24117: TM-score 0.99, RMSD 0.30 Å
- 3DVP chain A against the predicted model Q24117: TM-score 0.99, RMSD 0.31 Å
- 3DVP chain A against the predicted model Q24117: TM-score 0.99, RMSD 0.31 Å
- 4QH7 chain B against the predicted model Q24117: TM-score 0.99, RMSD 0.31 Å
- 4QH7 chain B against the predicted model Q24117: TM-score 0.99, RMSD 0.31 Å
- 4QH7 chain A against the predicted model Q24117: TM-score 0.99, RMSD 0.32 Å
- 4QH7 chain A against the predicted model Q24117: TM-score 0.99, RMSD 0.32 Å
- 4QH7 chain F against the predicted model Q24117: TM-score 0.99, RMSD 0.35 Å
- 4QH7 chain F against the predicted model Q24117: TM-score 0.99, RMSD 0.35 Å
Elsewhere
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