MolNFT v1 · #179313 · protein
Crystal structure of the second bromodomain (BD2) of human TAF1 bound to bromosporine
7K1P · Transcription initiation factor tfiid subunit 1: “Crystal structure of the second bromodomain (BD2) of human TAF1 bound to bromosporine”. X-ray diffraction, 1 ligand (BMF), 1 pocket (best druggability 0.51). MolNFT v1 #179313 on…
- PDB
- 7K1P
- Type
- protein
- Length
- 130 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcription initiation factor tfiid subunit 1
- EC
- 2.3.1.48, 2.7.11.1
- UniProt
- P21675
- Ligands
- BMF
- Pockets
- 1 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 68% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription initiation factor tfiid subunit 1 (EC 2.3.1.48, 2.7.11.1) | protein | 130 | 68% helix, 0% strand | P21675 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 97 | 0.51 | 0.82 | 19 | BMF |
Compared structures
- 7K1P · Crystal structure of the second bromodomain (BD2) of human TAF1 bound to bromosporine · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21675
- Elsewhere: RCSB PDB 7K1P · PDBe 7K1P · UniProt P21675
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