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MolNFT v1 · #179219 · protein

Solution NMR structure and dynamics of human BRD3 et in complex with mlv in ctd

7JYZ · Integrase: “Solution NMR structure and dynamics of human BRD3 et in complex with mlv in ctd”. Solution nmr. MolNFT v1 #179219 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7JYZ
Type
protein
Length
185 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Integrase; Bromodomain-containing protein 3
EC
2.7.7.49, 2.7.7.7, 3.1.26.4
UniProt
Q8UN00, Q15059

Structure

solution nmr · 2 distinct chains · 24% helix, 22% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AIntegrase (EC 2.7.7.49, 2.7.7.7, 3.1.26.4)protein893% helix, 42% strandQ8UN00
BBromodomain-containing protein 3protein9643% helix, 4% strandQ15059

Interfaces

1 interface between chains.

  • A–B · 799 Ų buried · 14 hydrogen bonds · protein-protein

Compared structures

  • 7JYZ · Solution NMR structure and dynamics of human Brd3 ET in complex with MLV IN CTD · the same entry in another collection · chain A against A, TM-score 1.00
  • Q15059 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 3 (Q15059) · a predicted model of the same protein · chain B against A, TM-score 0.62

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