MolNFT v1 · #179185 · protein
Anth domain of calm (clathrin-assembly lymphoid myeloid leukemia protein) bound to ubiquitin
7JXV · Phosphatidylinositol-binding clathrin assembly protein: “Anth domain of calm (clathrin-assembly lymphoid myeloid leukemia protein) bound to ubiquitin”. X-ray diffraction, 1 pocket (best druggability 0.31). MolNFT v1 #179185 on…
- PDB
- 7JXV
- Type
- protein
- Length
- 342 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphatidylinositol-binding clathrin assembly protein; Ubiquitin
- UniProt
- O55012, P0CG48
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 2 distinct chains · 61% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol-binding clathrin assembly protein | protein | 268 | 72% helix, 0% strand | O55012 |
| B | Ubiquitin | protein | 74 | 24% helix, 35% strand | P0CG48 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 73 | 0.31 | 0.73 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 685 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 7JXV · ANTH domain of CALM (clathrin-assembly lymphoid myeloid leukemia protein) bound to… · the same entry in another collection · chain A against A, TM-score 1.00
- O55012 · AlphaFold monomer V2.0 prediction for phosphatidylinositol-binding clathrin assembly… · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O55012
- Every structure of UniProt P0CG48
- Elsewhere: RCSB PDB 7JXV · PDBe 7JXV · UniProt O55012 · UniProt P0CG48
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