MolNFT v1 · #179178 · protein
Triangular trimer of beta-hairpins derived from ABETA17-36 with an F20CHA mutation
7JXO · Amyloid-beta 17-36 peptide: “Triangular trimer of beta-hairpins derived from ABETA17-36 with an F20CHA mutation”. X-ray diffraction. MolNFT v1 #179178 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7JXO
- Type
- protein
- Length
- 63 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Amyloid-beta 17-36 peptide
- UniProt
- P05067
Structure
x-ray diffraction · 1 distinct chain · 0% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Amyloid-beta 17-36 peptide | protein | 21 | 0% helix, 48% strand | P05067 |
Interfaces
3 interfaces between chains.
- B–C · 206 Ų buried · 2 hydrogen bonds · protein-protein
- A–B · 192 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 188 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 9 modified, 3 disulfide (nonstandard, disulfide).
Compared structures
- 7JXO · Triangular trimer of beta-hairpins derived from Abeta17-36 with an F20Cha mutation · the same entry in another collection · chain A against A, TM-score 1.00
- P05067 · AlphaFold monomer V2.0 prediction for amyloid-beta precursor protein (P05067) · a predicted model of the same protein · chain C against A, TM-score 0.33
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05067
- Elsewhere: RCSB PDB 7JXO · PDBe 7JXO · UniProt P05067
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