MolNFT v1 · #179026 · protein
Crystal structure of bptf bromodomain labelled with 5-fluoro- tryptophan
7JT4 · Nucleosome-remodeling factor subunit bptf: “Crystal structure of bptf bromodomain labelled with 5-fluoro- tryptophan”. X-ray diffraction, 1 pocket (best druggability 0.51). MolNFT v1 #179026 on GenesisL1: 3D structure, binding sites…
- PDB
- 7JT4
- Type
- protein
- Length
- 122 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nucleosome-remodeling factor subunit bptf
- UniProt
- Q12830
- Pockets
- 1 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 67% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleosome-remodeling factor subunit bptf | protein | 122 | 67% helix, 0% strand | Q12830 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 87 | 0.51 | 0.83 | 18 | empty |
Modifications
Observed in the structure: 1 modified (nonstandard).
Compared structures
- 7JT4 · Crystal Structure of BPTF bromodomain labelled with 5-fluoro-tryptophan · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12830
- Elsewhere: RCSB PDB 7JT4 · PDBe 7JT4 · UniProt Q12830
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