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MolNFT v1 · #178454 · DNA

Discovery of DS15060524; gene targeting chimera (genetac) for the treatment of FRIEDREICH'S ataxia (frda)

7FGT: “Discovery of DS15060524; gene targeting chimera (genetac) for the treatment of FRIEDREICH'S ataxia (frda)”. Solution nmr, 1 ligand (5R3). MolNFT v1 #178454 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7FGT
Type
DNA
Length
18 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Ligands
5R3

Structure

solution nmr · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—dna9——
B—dna9——

Ligands and binding sites

  • 5R3 · ~{N}-[3-[3-(dimethylamino)propylamino]-3-oxidanylidene-propyl]-1-methyl-4-[3-[[1-methyl-4-[[1-methyl-4-[3-[[1-methyl-4-[(1-methylimidazol-2-yl) carbonylamino]pyrrol-2-yl]carbonylamino]propanoylamino]imidazol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]propanoylamino]imidazole-2-carboxamide · ligand · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7FGT · Discovery of DS15060524; Gene targeting chimera (GeneTAC) for the treatment of… · the same entry in another collection · chain A against A, TM-score 1.00

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