MolNFT v1 · #178347 · protein

Cryo-EM structure of an alphavirus, getah virus

7FD2: “Cryo-EM structure of an alphavirus, getah virus”. Electron microscopy, 7 ligands (PLM, CLR, STE). MolNFT v1 #178347 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7FD2
Type: protein
Length: 4,060 residues
Chains: 12
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: A0A1Z2R994
Ligands: PLM, CLR, STE, PCW, NAG, BMA, MAN

Structure

electron microscopy · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, E, I, M	—	protein	438	—	A0A1Z2R994
B, F, J, N	—	protein	419	—	A0A1Z2R994
C, G, K, O	—	protein	158	—	A0A1Z2R994

Ligands and binding sites

PLM · Palmitic acid · ligand · 12 copies · chains A, B, E, F, I, J, M, N
CLR · Cholesterol · ligand · 12 copies · chains A, B, E, F, I, J, M, N
STE · Stearic acid · ligand · 8 copies · chains A, B, E, F, I, J, M, N
PCW · 1,2-dioleoyl-sn-glycero-3-phosphocholine · ligand · 4 copies · chains A, B, E, F, I, J, M, N
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 28 copies · chains A, B, E, F, I, J, M, N
BMA · beta-D-mannopyranose · sugar · 8 copies · chains E, M
MAN · alpha-D-mannopyranose · sugar · 4 copies · chains E, I

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7FD2 · Cryo-EM structure of an alphavirus, Getah virus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A1Z2R994
Elsewhere: RCSB PDB 7FD2 · PDBe 7FD2 · UniProt A0A1Z2R994

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