MolNFT v1 · #178206 · protein
Crystal structure of protein pitb from pilus islet-2 of streptococcus pneumoniae
7F7Y: “Crystal structure of protein pitb from pilus islet-2 of streptococcus pneumoniae”. X-ray diffraction, 3 ligands (K, IOD, SO4), 4 pockets (best druggability 0.55). MolNFT v1 #178206 on GenesisL1: 3D structure, binding sites and…
- PDB
- 7F7Y
- Type
- protein
- Length
- 664 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pitb
- UniProt
- B3FNT1
- Ligands
- K, IOD, SO4
- Pockets
- 4 · best druggability 0.55
Structure
x-ray diffraction · 1 distinct chain · 2% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Pitb | protein | 332 | 2% helix, 48% strand | B3FNT1 |
Ligands and binding sites
- K · Potassium ion · metal · 3 copies · chains B
- IOD · Iodide ion · ion · 9 copies · chains A, B
- SO4 · Sulfate ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 385 | 0.55 | 0.74 | 39 | IOD, K |
| 2 | 121 | 0.44 | 0.77 | 22 | empty |
| 3 | 84 | 0.40 | 0.78 | 21 | empty |
| 4 | 50 | 0.25 | 0.73 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 194 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 isopeptide (isopeptide).
Compared structures
- 7F7Y · Crystal Structure of protein PitB from pilus islet-2 of Streptococcus pneumoniae · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B3FNT1
- Elsewhere: RCSB PDB 7F7Y · PDBe 7F7Y · UniProt B3FNT1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.