MolNFT v1 · #177975 · protein
Crystal structure of human PIN1 complexed with a potent covalent inhibitor
7F0M: “Crystal structure of human PIN1 complexed with a potent covalent inhibitor”. X-ray diffraction, 1 ligand (0BF). MolNFT v1 #177975 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7F0M
- Type
- protein
- Length
- 584 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q13526
- Ligands
- 0BF
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | — | protein | 146 | — | Q13526 |
Ligands and binding sites
- 0BF · 8-(2-chloranylethanoyl)-4-[(5-naphthalen-1-ylfuran-2-yl)methyl]-1-thia-4,8-diazaspiro[4.5]decan-3-one · ligand · 4 copies · chains A, C, B, D
- P33 · 3,6,9,12,15,18-hexaoxaicosane-1,20-diol · additive · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7F0M · Crystal Structure of human Pin1 complexed with a potent covalent inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13526
- Elsewhere: RCSB PDB 7F0M · PDBe 7F0M · UniProt Q13526
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