MolNFT v1 · #177396 · protein
Crystal structure of the flagellar hook cap from salmonella enterica serovar typhimurium
7EHA · Basal-body rod modification protein flgd: “Crystal structure of the flagellar hook cap from salmonella enterica serovar typhimurium”. X-ray diffraction, 9 pockets (best druggability 0.79). MolNFT v1 #177396 on GenesisL1: 3D…
- PDB
- 7EHA
- Type
- protein
- Length
- 824 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Basal-body rod modification protein flgd
- UniProt
- P0A1I9
- Pockets
- 9 · best druggability 0.79
Structure
x-ray diffraction · 5 distinct chains · 22% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Basal-body rod modification protein flgd | protein | 177 | 24% helix, 41% strand | P0A1I9 |
| B | Basal-body rod modification protein flgd | protein | 165 | 22% helix, 41% strand | P0A1I9 |
| C | Basal-body rod modification protein flgd | protein | 162 | 23% helix, 42% strand | P0A1I9 |
| D | Basal-body rod modification protein flgd | protein | 154 | 20% helix, 36% strand | P0A1I9 |
| E | Basal-body rod modification protein flgd | protein | 166 | 19% helix, 45% strand | P0A1I9 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1010 | 0.79 | 0.81 | 57 | empty |
| 2 | 258 | 0.65 | 0.82 | 36 | empty |
| 3 | 86 | 0.59 | 0.88 | 22 | empty |
| 4 | 125 | 0.55 | 0.83 | 21 | empty |
| 5 | 280 | 0.52 | 0.74 | 30 | empty |
Interfaces
5 interfaces between chains.
- A–B · 1116 Ų buried · 14 hydrogen bonds · protein-protein
- D–E · 925 Ų buried · 8 hydrogen bonds · protein-protein
- C–D · 889 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 706 Ų buried · 7 hydrogen bonds · protein-protein
- A–E · 617 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 7EHA · Crystal structure of the flagellar hook cap from Salmonella enterica serovar Typhimurium · the same entry in another collection · chain E against E, TM-score 1.00
- P0A1I9 · AlphaFold monomer V2.0 prediction for basal-body rod modification protein flgd (P0A1I9) · a predicted model of the same protein · chain C against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A1I9
- Elsewhere: RCSB PDB 7EHA · PDBe 7EHA · UniProt P0A1I9
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