MolNFT v1 · #177379 · protein
X-ray structure of the human heart fatty acid-binding protein complexed with the fluorescent probe HA527
7EGO · Fatty acid-binding protein, heart: “X-ray structure of the human heart fatty acid-binding protein complexed with the fluorescent probe HA527”. X-ray diffraction, 1 ligand (J3R), 1 pocket (best druggability 0.84). MolNFT v1 #177379…
- PDB
- 7EGO
- Type
- protein
- Length
- 132 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fatty acid-binding protein, heart
- UniProt
- P05413
- Ligands
- J3R
- Pockets
- 1 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 14% helix, 58% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fatty acid-binding protein, heart | protein | 132 | 14% helix, 58% strand | P05413 |
Ligands and binding sites
- J3R · 3-[methyl-(4-nitro-2,1,3-benzoxadiazol-7-yl) amino]propanoic acid · ligand · chains A
- P6G · Hexaethylene glycol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 287 | 0.84 | 0.95 | 34 | J3R |
Compared structures
- 7EGO · X-ray structure of the human heart fatty acid-binding protein complexed with the… · the same entry in another collection · chain A against A, TM-score 1.00
- P05413 · AlphaFold monomer V2.0 prediction for fatty acid-binding protein, heart (P05413) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05413
- Elsewhere: RCSB PDB 7EGO · PDBe 7EGO · UniProt P05413
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