UniProt P05413
Fatty acid-binding protein, heart (P05413)
Fatty acid-binding protein, heart (UniProt P05413): 71 experimental structures and 1 predicted model on GenesisL1, 33 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P05413
- Protein
- Fatty acid-binding protein, heart
- Experimental structures
- 71
- Predicted models
- 1
- Ligands
- 33
- Pockets
- 9 · 9 records with a druggable one
Structures
72 records of P05413 in the MolNFT archive: 71 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1G5W | Solution structure of human heart-type fatty acid binding protein | solution nmr | A | — | — |
| 1G5W | Solution structure of human heart-type fatty acid binding protein | solution nmr | A | — | — |
| 1HMR | 1.4 ångströms structural studies on human muscle fatty acid binding protein: binding interactions… | x-ray diffraction | A | — | — |
| 1HMR | 1.4 ångströms structural studies on human muscle fatty acid binding protein: binding interactions… | x-ray diffraction | A | — | — |
| 1HMS | 1.4 ångströms structural studies on human muscle fatty acid binding protein: binding interactions… | x-ray diffraction | A | — | — |
| 1HMS | 1.4 ångströms structural studies on human muscle fatty acid binding protein: binding interactions… | x-ray diffraction | A | — | — |
| 1HMT | 1.4 ångströms structural studies on human muscle fatty acid binding protein: binding interactions… | x-ray diffraction | A | — | — |
| 1HMT | 1.4 ångströms structural studies on human muscle fatty acid binding protein: binding interactions… | x-ray diffraction | A | — | — |
| 2HMB | Three-dimensional structure of recombinant human muscle fatty acid-binding protein | x-ray diffraction | A | — | — |
| 2HMB | Three-dimensional structure of recombinant human muscle fatty acid- binding protein | x-ray diffraction | A | — | — |
| 3RSW | Crystal Structure of Heart Fatty Acid Binding Protein (FABP3) | x-ray diffraction | A, B | — | — |
| 3RSW | Crystal structure of heart fatty acid binding protein (FABP3) | x-ray diffraction | A, B | — | — |
| 3WBG | Structure of the human heart fatty acid-binding protein in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 3WBG | Structure of the human heart fatty acid-binding protein in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 3WVM | The 0.88 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with… | x-ray diffraction | A | — | — |
| 3WVM | The 0.88 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | — | — |
| 3WXQ | Serial femtosecond X-ray structure of human fatty acid-binding protein type-3 (FABP3) in complex… | x-ray diffraction | A | — | — |
| 3WXQ | Serial femtosecond X-ray structure of human fatty acid-binding protein type-3 (FABP3) in complex… | x-ray diffraction | A | — | — |
| 4TJZ | The 0.87 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with… | x-ray diffraction | A | — | — |
| 4TJZ | The 0.87 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | — | — |
| 4TKB | The 0.86 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with… | x-ray diffraction | A | — | — |
| 4TKB | The 0.86 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | — | — |
| 4TKH | The 0.93 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with… | x-ray diffraction | A | — | — |
| 4TKH | The 0.93 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | — | — |
| 4TKJ | The 0.87 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with… | x-ray diffraction | A | — | — |
| 4TKJ | The 0.87 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | — | — |
| 4WBK | The 1.37 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with… | x-ray diffraction | A | — | — |
| 4WBK | The 1.37 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | — | — |
| 5B27 | The 1.02A structure of human FABP3 M20S mutant complexed with palmitic acid | x-ray diffraction | A | — | — |
| 5B27 | The 1.02A structure of human FABP3 M20S mutant complexed with palmitic acid | x-ray diffraction | A | — | — |
| 5B28 | The 0.90A structure of human FABP3 F16V mutant complexed with palmitic acid | x-ray diffraction | A | PLM | 1 (best 0.84) |
| 5B28 | The 0.90A structure of human FABP3 F16V mutant complexed with palmitic acid | x-ray diffraction | A | — | — |
| 5B29 | The 1.28A structure of human FABP3 F16V mutant complexed with palmitic acid at room temperature | x-ray diffraction | A | — | — |
| 5B29 | The 1.28A structure of human FABP3 F16V mutant complexed with palmitic acid at room temperature | x-ray diffraction | A | — | — |
| 5CE4 | High resolution X-ray and neutron diffraction structure of H-fabp | x-ray diffraction; neutron diffraction | A | — | — |
| 5HZ9 | Human FABP3 in complex with 6-chloro-2-methyl-4-phenyl-quinoline-3- carboxylic acid | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 6AQ1 | The crystal structure of human FABP3 | x-ray diffraction | A, B | SO4, PLM | — |
| 6AQ1 | The crystal structure of human FABP3 | x-ray diffraction | A, B | SO4, PLM | — |
| 7EGO | X-ray structure of the human heart fatty acid-binding protein complexed with the fluorescent probe… | x-ray diffraction | A | J3R | — |
| 7EUV | X-ray structure of high-strength hydrogel-grown FABP3 crystal soaked in 50% DMSO solution… | x-ray diffraction | A | FLR | 1 (best 0.80) |
| 7EUV | X-ray structure of high-strength hydrogel-grown FABP3 crystal soaked in 50% dmso solution… | x-ray diffraction | A | FLR | — |
| 7EUW | X-ray structure of high-strength hydrogel-grown FABP3 crystal soaked in 50% DMSO solution… | x-ray diffraction | A | JEC, SO3 | — |
| 7EUW | X-ray structure of high-strength hydrogel-grown FABP3 crystal soaked in 50% dmso solution… | x-ray diffraction | A | JEC, SO3 | — |
| 7FBF | The 0.86 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | OCA | — |
| 7FBM | X-ray structure of high-strength hydrogel-grown FABP3 crystal soaked in 50% dmso solution… | x-ray diffraction | A | 3IM | — |
| 7FBN | X-ray structure of high-strength hydrogel-grown FABP3 crystal soaked in 50% dmf solution containing… | x-ray diffraction | A | 3IM | — |
| 7FC4 | X-ray structure of the human heart fatty acid-binding protein complexed with S-ibuprofen | x-ray diffraction | A | IBP | — |
| 7FCG | X-ray structure of high-strength hydrogel-grown FABP3 crystal soaked in 50% dmso solution… | x-ray diffraction | A | IMN | — |
| 7FCX | Room temperature structure of the human heart fatty acid-binding protein complexed with hexanoic… | x-ray diffraction | A | 6NA | — |
| 7FD7 | The 1.00 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | 4EI | — |
| 7FDT | The 0.86 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | ELA | — |
| 7FDU | The 0.86 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | X90 | — |
| 7FDX | X-ray structure of the human heart fatty acid-binding protein complexed with the fluorescent probe… | x-ray diffraction | A | 2AN | — |
| 7FEK | The 1.05 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | 8PF | — |
| 7FEU | The 0.95 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | 4I6 | — |
| 7FEZ | The 0.76 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | 4I1 | — |
| 7FF6 | The 0.83 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | 4IF, GLP | — |
| 7FFK | The 0.84 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with… | x-ray diffraction | A | PAM | 1 (best 0.83) |
| 7FFK | The 0.84 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | PAM | — |
| 7FFX | The 0.88 ångström X-ray structure of the human heart fatty acid- binding protein complexed with… | x-ray diffraction | A | LNL, GLP | — |
12 records more on the page itself.
Ligands
- PLM · Palmitic acid · in 4 records
- 3IM · 2,6-ditert-butyl-4-methyl-phenol · in 2 records
- FLR · (2R)-2-(3-fluoro-4-phenyl-phenyl)propanoic acid · in 2 records
- GLP · 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose · in 2 records
- JEC · 4-[2-[1-(4-bromophenyl)-5-phenyl-pyrazol-3-yl]phenoxy]butanoic acid · in 2 records
- PAM · Palmitoleic acid · in 2 records
- SO3 · Sulfite ion · in 2 records
- SO4 · Sulfate ion · in 2 records
- 08O · (Z)-docos-13-enoic acid · in 1 record
- 11A · Undecanoic acid · in 1 record
- 2AN · 8-anilino-1-naphthalene sulfonate · in 1 record
- 4EI · Perfluoroheptanoic acid · in 1 record
- 4I1 · Petroselinic acid · in 1 record
- 4I6 · Perfluorononanoic acid · in 1 record
- 4IF · Cis-vaccenic acid · in 1 record
- 6NA · Hexanoic acid · in 1 record
- 8PF · pentadecafluorooctanoic acid · in 1 record
- ACD · Arachidonic acid · in 1 record
- DKA · Decanoic acid · in 1 record
- ELA · 9-octadecenoic acid · in 1 record
- EPA · 5,8,11,14,17-eicosapentaenoic acid · in 1 record
- HA4 · 2-cyclohexadecylethanoic acid · in 1 record
- HXA · Docosa-4,7,10,13,16,19-hexaenoic acid · in 1 record
- IBP · Ibuprofen · in 1 record
- IMN · Indomethacin · in 1 record
- J1W · 2-Bromopalmitic acid · in 1 record
- J3R · 3-[methyl-(4-nitro-2,1,3-benzoxadiazol-7-yl) amino]propanoic acid · in 1 record
- LNL · Alpha-linolenic acid · in 1 record
- NER · (15E)-tetracos-15-enoic acid · in 1 record
- OCA · Octanoic acid (caprylic acid) · in 1 record
Experiment against prediction
- 5CE4 chain A against the predicted model P05413: TM-score 0.99, RMSD 0.35 Å
- 1HMT chain A against the predicted model P05413: TM-score 0.99, RMSD 0.36 Å
- 1HMT chain A against the predicted model P05413: TM-score 0.99, RMSD 0.36 Å
- 3WXQ chain A against the predicted model P05413: TM-score 0.99, RMSD 0.37 Å
- 3WXQ chain A against the predicted model P05413: TM-score 0.99, RMSD 0.37 Å
- 5B29 chain A against the predicted model P05413: TM-score 0.99, RMSD 0.37 Å
- 5B29 chain A against the predicted model P05413: TM-score 0.99, RMSD 0.37 Å
- 7FG5 chain A against the predicted model P05413: TM-score 0.99, RMSD 0.38 Å
- 1HMR chain A against the predicted model P05413: TM-score 0.99, RMSD 0.37 Å
- 1HMR chain A against the predicted model P05413: TM-score 0.99, RMSD 0.37 Å
Elsewhere
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