MolNFT v1 · #177095 · protein
Crystal structure of apo enl yeats domain T3 mutant
7E7A · Protein enl: “Crystal structure of apo enl yeats domain T3 mutant”. X-ray diffraction, 5 pockets (best druggability 0.77). MolNFT v1 #177095 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7E7A
- Type
- protein
- Length
- 550 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein enl
- UniProt
- Q03111
- Pockets
- 5 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 9% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D | Protein enl | protein | 137 | 9% helix, 53% strand | Q03111 |
| B, C | Protein enl | protein | 138 | 9% helix, 52% strand | Q03111 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 636 | 0.77 | 0.82 | 67 | empty |
| 2 | 662 | 0.74 | 0.80 | 58 | empty |
| 3 | 328 | 0.64 | 0.80 | 36 | empty |
| 4 | 219 | 0.62 | 0.82 | 29 | empty |
| 5 | 55 | 0.28 | 0.74 | 13 | empty |
Interfaces
5 interfaces between chains.
- B–D · 596 Ų buried · 8 hydrogen bonds · protein-protein
- A–C · 582 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 498 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 323 Ų buried · 4 hydrogen bonds · protein-protein
- A–D · 265 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q03111
- Elsewhere: RCSB PDB 7E7A · PDBe 7E7A · UniProt Q03111
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