MolNFT v1 · #176673 · protein
Crystal structure of human proto-oncogene tyrosine-protein kinase receptor ret in complex with selpercatinib
7DU8: “Crystal structure of human proto-oncogene tyrosine-protein kinase receptor ret in complex with selpercatinib”. X-ray diffraction, 1 ligand (Q6G). MolNFT v1 #176673 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7DU8
- Type
- protein
- Length
- 565 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P07949
- Ligands
- Q6G
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 286 | — | P07949 |
| B | — | protein | 279 | — | P07949 |
Ligands and binding sites
- Q6G · Selpercatinib · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7DU8 · Crystal structure of human Proto-oncogene tyrosine-protein kinase receptor Ret in complex… · the same entry in another collection · chain A against A, TM-score 1.00
- P07949 · AlphaFold monomer V2.0 prediction for proto-oncogene tyrosine-protein kinase receptor ret… · a predicted model of the same protein · chain B against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07949
- Elsewhere: RCSB PDB 7DU8 · PDBe 7DU8 · UniProt P07949
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