MolNFT v1 · #176443 · protein

The crystal structure of CPD7 in complex with bptf bromodomain

7DMY · Nucleosome-remodeling factor subunit bptf: “The crystal structure of CPD7 in complex with bptf bromodomain”. X-ray diffraction, 1 ligand (HAF), 1 pocket (best druggability 0.50). MolNFT v1 #176443 on GenesisL1: 3D structure, binding…

PDB: 7DMY
Type: protein
Length: 119 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleosome-remodeling factor subunit bptf
UniProt: Q12830
Ligands: HAF
Pockets: 1 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 70% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleosome-remodeling factor subunit bptf	protein	119	70% helix, 0% strand	Q12830

Ligands and binding sites

HAF · tert-butyl 3-methyl-2-[[(3R,5R)-1-methyl-5-phenyl-piperidin-3-yl]amino]-4-oxidanylidene-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	98	0.50	0.82	20	HAF

Compared structures

7DMY · The crystal structure of Cpd7 in complex with BPTF bromodomain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q12830
Elsewhere: RCSB PDB 7DMY · PDBe 7DMY · UniProt Q12830

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