MolNFT v1 · #176343 · protein

The co-crystal structure of DYRK2 with a small molecule inhibitor 17

7DJO: “The co-crystal structure of DYRK2 with a small molecule inhibitor 17”. X-ray diffraction, 1 ligand (H80). MolNFT v1 #176343 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7DJO
Type: protein
Length: 324 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q92630
Ligands: H80

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	324	—	Q92630

Ligands and binding sites

H80 · [2,7-dimethoxy-9-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7DJO · The co-crystal structure of DYRK2 with a small molecule inhibitor 17 · the same entry in another collection · chain A against A, TM-score 1.00
Q92630 · AlphaFold monomer V2.0 prediction for dual specificity tyrosine… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92630
Elsewhere: RCSB PDB 7DJO · PDBe 7DJO · UniProt Q92630

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