MolNFT v1 · #17623 · protein
X-ray structure of acidic phospholipase A2 from indian saw- scaled viper (echis carinatus) with a potent platelet aggregation inhibitory activity
1OZ6: “X-ray structure of acidic phospholipase A2 from indian saw- scaled viper (echis carinatus) with a potent…”. X-ray diffraction, 1 ligand (CA), 1 pocket (best druggability 0.55). MolNFT v1 #17623 on GenesisL1: 3D structure, binding…
- PDB
- 1OZ6
- Type
- protein
- Length
- 120 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phospholipase A2
- EC
- 3.1.1.4
- UniProt
- Q7T3S7
- Ligands
- CA
- Pockets
- 1 · best druggability 0.55
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phospholipase A2 (EC 3.1.1.4) | protein | 120 | 48% helix, 7% strand | Q7T3S7 |
Ligands and binding sites
- CA · Calcium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 235 | 0.55 | 0.77 | 25 | CA |
Modifications
Observed in the structure: 7 disulfide (disulfide).
Compared structures
- 1OZ6 · X-ray structure of acidic phospholipase A2 from Indian saw-scaled viper (Echis carinatus)… · the same entry in another collection · chain A against A, TM-score 1.00
- Q7T3S7 · AlphaFold monomer V2.0 prediction for acidic phospholipase A2 ec-I (Q7T3S7) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7T3S7
- Elsewhere: RCSB PDB 1OZ6 · PDBe 1OZ6 · UniProt Q7T3S7
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