MolNFT v1 · #176091 · protein

Crystal structure of mycobacterium tuberculosis phenylalanyl-tRNA synthetase in complex with compound pf-3845

7DB8: “Crystal structure of mycobacterium tuberculosis phenylalanyl-tRNA synthetase in complex with compound pf-3845”. X-ray diffraction, 2 ligands (H2R, SO4). MolNFT v1 #176091 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7DB8
Type: protein
Length: 1,102 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P9WFU3, P9WFU1
Ligands: H2R, SO4

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	267	—	P9WFU3
B	—	protein	835	—	P9WFU1

Ligands and binding sites

H2R · N-pyridin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methyl]piperidine-1-carboxamide · ligand · chains A
SO4 · Sulfate ion · ion · 13 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7DB8 · Crystal structure of Mycobacterium tuberculosis phenylalanyl-tRNA synthetase in complex… · the same entry in another collection · chain A against A, TM-score 1.00
P9WFU1 · AlphaFold monomer V2.0 prediction for phenylalanine--tRNA ligase beta subunit (P9WFU1) · a predicted model of the same protein · chain B against A, TM-score 0.96
P9WFU3 · AlphaFold monomer V2.0 prediction for phenylalanine--tRNA ligase alpha subunit (P9WFU3) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P9WFU3
Every structure of UniProt P9WFU1
Elsewhere: RCSB PDB 7DB8 · PDBe 7DB8 · UniProt P9WFU3 · UniProt P9WFU1

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