MolNFT v1 · #175890 · protein
ATP complex with double mutant cyclic trinucleotide synthase cdnd
7D4U · Cyclic AMP-AMP-gmp synthase: “ATP complex with double mutant cyclic trinucleotide synthase cdnd”. X-ray diffraction, 1 ligand (ATP), 2 pockets (best druggability 0.74). MolNFT v1 #175890 on GenesisL1: 3D structure, binding sites and…
- PDB
- 7D4U
- Type
- protein
- Length
- 342 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cyclic AMP-AMP-gmp synthase
- EC
- 2.7.7.-
- UniProt
- P0DSP4
- Ligands
- ATP
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cyclic AMP-AMP-gmp synthase (EC 2.7.7.-) | protein | 342 | 48% helix, 12% strand | P0DSP4 |
Ligands and binding sites
- ATP · Adenosine-5'-triphosphate · ligand · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 842 | 0.74 | 0.78 | 57 | ATP |
| 2 | 55 | 0.35 | 0.78 | 12 | empty |
Compared structures
- 7D4U · ATP complex with double mutant cyclic trinucleotide synthase CdnD · the same entry in another collection · chain A against A, TM-score 1.00
- P0DSP4 · AlphaFold monomer V2.0 prediction for cyclic AMP-AMP-gmp synthase (P0DSP4) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0DSP4
- Elsewhere: RCSB PDB 7D4U · PDBe 7D4U · UniProt P0DSP4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.