MolNFT v1 · #175614 · protein

Crystal structure of beta-galactosidase II from bacillus circulans in complex with beta-D-galactopyranosyl disaccharide

7CWD · Beta-glalactosidase: “Crystal structure of beta-galactosidase II from bacillus circulans in complex with beta-D-galactopyranosyl…”. X-ray diffraction, 2 ligands (GAL, GLC), 7 pockets (best druggability 0.76). MolNFT v1 #175614 on…

PDB: 7CWD
Type: protein
Length: 803 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-glalactosidase
EC: 3.2.1.23
Ligands: GAL, GLC
Pockets: 7 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 14% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-glalactosidase (EC 3.2.1.23)	protein	803	14% helix, 39% strand	—

Ligands and binding sites

GAL · beta-D-galactopyranose · sugar · 2 copies · chains A
GLC · alpha-D-glucopyranose · sugar · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	69	0.76	0.99	21	empty
2	1010	0.75	0.78	86	empty
3	321	0.62	0.79	26	empty
4	239	0.56	0.78	28	empty
5	157	0.49	0.78	26	empty

Compared structures

7CWD · Crystal structure of beta-galactosidase II from Bacillus circulans in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7CWD · PDBe 7CWD

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