MolNFT v1 · #175589 · protein
Crystal structure of glucose isomerase by fixed-target serial synchrotron crystallography (100 ms)
7CVK · Xylose isomerase: “Crystal structure of glucose isomerase by fixed-target serial synchrotron crystallography (100 ms)”. X-ray diffraction, 1 ligand (MG), 4 pockets (best druggability 0.73). MolNFT v1 #175589 on GenesisL1: 3D…
- PDB
- 7CVK
- Type
- protein
- Length
- 385 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Xylose isomerase
- EC
- 5.3.1.5
- UniProt
- P24300
- Ligands
- MG
- Pockets
- 4 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Xylose isomerase (EC 5.3.1.5) | protein | 385 | 50% helix, 10% strand | P24300 |
Ligands and binding sites
- MG · Magnesium ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.73 | 0.99 | 24 | empty |
| 2 | 518 | 0.67 | 0.78 | 51 | empty |
| 3 | 88 | 0.48 | 0.82 | 14 | empty |
| 4 | 54 | 0.33 | 0.77 | 13 | empty |
Compared structures
- 7CVK · Crystal structure of glucose isomerase by fixed-target serial synchrotron crystallography… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24300
- Elsewhere: RCSB PDB 7CVK · PDBe 7CVK · UniProt P24300
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.