MolNFT v1 · #1755 · protein
Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 ångströms resolution
1BBC: “Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 ångströms…”. X-ray diffraction, 1 pocket (best druggability 0.49). MolNFT v1 #1755 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1BBC
- Type
- protein
- Length
- 124 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phospholipase A2
- EC
- 3.1.1.4
- UniProt
- P14555
- Pockets
- 1 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phospholipase A2 (EC 3.1.1.4) | protein | 124 | 44% helix, 6% strand | P14555 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 135 | 0.49 | 0.79 | 20 | empty |
Modifications
Observed in the structure: 7 disulfide (disulfide).
Compared structures
- 1BBC · Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at… · the same entry in another collection · chain A against A, TM-score 1.00
- P14555 · AlphaFold monomer V2.0 prediction for phospholipase A2, membrane associated (P14555) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14555
- Elsewhere: RCSB PDB 1BBC · PDBe 1BBC · UniProt P14555
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