MolNFT v1 · #175057 · protein

Crystal structure of cysteine desulfurase sufs H121A from bacillus subtilis

7CEQ: “Crystal structure of cysteine desulfurase sufs H121A from bacillus subtilis”. X-ray diffraction, 1 pocket (best druggability 0.37). MolNFT v1 #175057 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7CEQ
Type: protein
Length: 414 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cysteine desulfurase sufs
EC: 2.8.1.7
UniProt: O32164
Pockets: 1 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cysteine desulfurase sufs (EC 2.8.1.7)	protein	414	45% helix, 18% strand	O32164

Ligands and binding sites

PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	71	0.37	0.78	15	empty

Modifications

Observed in the structure: 1 modified (cofactor).

Compared structures

7CEQ · Crystal structure of cysteine desulfurase SufS H121A from Bacillus subtilis · the same entry in another collection · chain A against A, TM-score 1.00
O32164 · AlphaFold monomer V2.0 prediction for cysteine desulfurase sufs (O32164) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O32164
Elsewhere: RCSB PDB 7CEQ · PDBe 7CEQ · UniProt O32164

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