MolNFT v1 · #174521 · protein

Toxin-antitoxin complex from klebsiella pneumoniae

7BY2 · Copg family transcriptional regulator: “Toxin-antitoxin complex from klebsiella pneumoniae”. X-ray diffraction, 1 pocket (best druggability 0.58). MolNFT v1 #174521 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7BY2
Type: protein
Length: 150 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Copg family transcriptional regulator; Ribonuclease vapc
EC: 3.1.-.-
UniProt: W9BQC4, A0A0W8AM92
Pockets: 1 · best druggability 0.58

Structure

x-ray diffraction · 2 distinct chains · 53% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Copg family transcriptional regulator	protein	30	43% helix, 0% strand	W9BQC4
B	Ribonuclease vapc (EC 3.1.-.-)	protein	120	56% helix, 12% strand	A0A0W8AM92

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	99	0.58	0.85	23	empty

Interfaces

1 interface between chains.

A–B · 735 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 modified (engineered).

Compared structures

7BY2 · Toxin-antitoxin complex from Klebsiella pneumoniae · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt W9BQC4
Every structure of UniProt A0A0W8AM92
Elsewhere: RCSB PDB 7BY2 · PDBe 7BY2 · UniProt W9BQC4 · UniProt A0A0W8AM92

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