MolNFT v1 · #174515 · protein
Crystal structure off RTT109 from candida albicans
7BXW · Histone acetyltransferase RTT109: “Crystal structure off RTT109 from candida albicans”. X-ray diffraction, 1 ligand (ACM), 3 pockets (best druggability 0.73). MolNFT v1 #174515 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 7BXW
- Type
- protein
- Length
- 312 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Histone acetyltransferase RTT109
- EC
- 2.3.1.48
- UniProt
- Q5AAJ8
- Ligands
- ACM
- Pockets
- 3 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Histone acetyltransferase RTT109 (EC 2.3.1.48) | protein | 312 | 30% helix, 28% strand | Q5AAJ8 |
Ligands and binding sites
- ACM · Acetamide · ligand · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 308 | 0.73 | 0.85 | 43 | empty |
| 2 | 119 | 0.37 | 0.73 | 21 | empty |
| 3 | 58 | 0.26 | 0.73 | 16 | empty |
Modifications
Observed in the structure: 6 modified (engineered, acetylation).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5AAJ8
- Elsewhere: RCSB PDB 7BXW · PDBe 7BXW · UniProt Q5AAJ8
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