UniProt Q5AAJ8
Histone acetyltransferase RTT109 (Q5AAJ8)
Histone acetyltransferase RTT109 (UniProt Q5AAJ8), EC 2.3.1.48: 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 33 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q5AAJ8
- Protein
- Histone acetyltransferase RTT109
- EC
- 2.3.1.48
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 33 · 7 records with a druggable one
Structures
13 records of Q5AAJ8 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7BWZ | Crystal structure of RTT109 from CANDIDA ALBICANS | x-ray diffraction | A | — | 5 (best 0.74) |
| 7BWZ | Crystal structure of RTT109 from candida albicans | x-ray diffraction | A | — | — |
| 7BX0 | Crystal structure of RTT109 from Candida albicans | x-ray diffraction | A | — | — |
| 7BX0 | Crystal structure of RTT109 from candida albicans | x-ray diffraction | A | — | — |
| 7BX1 | Crystal structure of RTT109 from Candida albicans | x-ray diffraction | A | ACM | 4 (best 0.68) |
| 7BX1 | Crystal structure of RTT109 from candida albicans | x-ray diffraction | A | ACM | — |
| 7BXW | Crystal structure ofF RTT109 FROM Candida albicans | x-ray diffraction | A | ACM | 3 (best 0.73) |
| 7BXW | Crystal structure off RTT109 from candida albicans | x-ray diffraction | A | ACM | — |
| 7C3O | Crystal structure of TT109 from CANDIDA ALBICANS | x-ray diffraction | A | ACO | 7 (best 0.74) |
| 7C3O | Crystal structure of TT109 from candida albicans | x-ray diffraction | A | ACO | — |
| 8GQ3 | RTT109 mutant from Candida albicans | x-ray diffraction | A | — | 5 (best 0.75) |
| 8GQ4 | Histone acetyltransferase Rtt109 mutant-N195A | x-ray diffraction | A | — | 4 (best 0.73) |
| Q5AAJ8 | AlphaFold monomer V2.0 prediction for histone acetyltransferase RTT109 (Q5AAJ8) | predicted | A | — | 5 (best 0.68) |
Ligands
Experiment against prediction
- 7C3O chain A against the predicted model Q5AAJ8: TM-score 0.99, RMSD 0.76 Å
- 7C3O chain A against the predicted model Q5AAJ8: TM-score 0.99, RMSD 0.76 Å
- 7BXW chain A against the predicted model Q5AAJ8: TM-score 0.99, RMSD 0.79 Å
- 7BXW chain A against the predicted model Q5AAJ8: TM-score 0.99, RMSD 0.79 Å
- 7BX1 chain A against the predicted model Q5AAJ8: TM-score 0.99, RMSD 0.79 Å
- 7BX1 chain A against the predicted model Q5AAJ8: TM-score 0.99, RMSD 0.79 Å
- 8GQ4 chain A against the predicted model Q5AAJ8: TM-score 0.99, RMSD 0.80 Å
- 7BWZ chain A against the predicted model Q5AAJ8: TM-score 0.99, RMSD 0.81 Å
- 7BWZ chain A against the predicted model Q5AAJ8: TM-score 0.99, RMSD 0.81 Å
- 7BX0 chain A against the predicted model Q5AAJ8: TM-score 0.98, RMSD 0.83 Å
Elsewhere
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