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MolNFT v1 · #174094 · protein + RNA

Cryoem structure of MDA5-dsrna filament in complex with ADP with 92- degree helical twist

7BKQ: “Cryoem structure of MDA5-dsrna filament in complex with ADP with 92- degree helical twist”. Electron microscopy, 2 ligands (ADP, ZN). MolNFT v1 #174094 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7BKQ
Type
protein + RNA
Length
670 residues
Chains
3
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q8R5F7
Ligands
ADP, ZN

Structure

electron microscopy · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein640—Q8R5F7
X—rna15——
Y—rna15——

Ligands and binding sites

  • ADP · Adenosine-5'-diphosphate · ligand · chains A
  • ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7BKQ · CryoEM structure of MDA5-dsRNA filament in complex with ADP with 92-degree helical twist · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8R5F7 · AlphaFold monomer V2.0 prediction for interferon-induced helicase C domain-containing… · a predicted model of the same protein · chain A against A, TM-score 0.97

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